Manufacturer copay cards and patient assistance programs for the medicines used to treat skin cancer — grouped by drug class, with every program in a class listed side by side.
Almost every branded skin cancer drug has some form of cost help from its maker. There are two kinds, and which one applies to you depends on your insurance:
Dollar figures, phone numbers, and eligibility rules change often. Treat every entry as a starting point and confirm the current terms with the program directly.
For each drug class, we list every manufacturer’s program — not only the drug a visitor came looking for. If one Hedgehog pathway inhibitor is here, both are. If one PDT photosensitizer is here, all are. If one BRAF/MEK combination is here, all three are.
This site takes no payment from any manufacturer for inclusion, placement, or wording on this page, and no program listed here has reviewed or approved it. Listing a program is not a recommendation of that product; treatment choices belong with you and your physician.
Creams, gels, and ointments applied at home to treat actinic keratoses and, for some agents, superficial basal cell carcinoma or Bowen disease. Most are available as low-cost generics; the newer branded agents carry manufacturer savings programs.
Used in skin cancer for: Actinic keratosis.
Commercial insurance: Available as a generic on most formularies. No dedicated manufacturer program; a pharmacy discount card (GoodRx, SingleCare, NeedyMeds) is usually the lowest cash price.
Used in skin cancer for: Actinic keratosis; Efudex is also used for superficial basal cell carcinoma.
Commercial insurance: Generic 5-FU cream is inexpensive and widely covered. There is no single manufacturer assistance program; Tolak (Mayne Pharma) has periodically offered a commercial copay coupon.
Uninsured or underinsured: Use a pharmacy discount card (GoodRx, SingleCare, NeedyMeds) or ask the prescriber to write for generic fluorouracil.
Used in skin cancer for: Actinic keratosis; imiquimod 5% is also used for superficial basal cell carcinoma.
Commercial insurance: Generic imiquimod 5% is low-cost. Zyclara (3.75% / 2.5%) is brand-only and Bausch Health does not publish a patient assistance program for it — ask the pharmacy for a discounted cash price (GoodRx, SingleCare, NeedyMeds) or the prescriber about generic imiquimod.
Phone: 1-800-321-4576 (Bausch Health)
Used in skin cancer for: Actinic keratosis of the face or scalp (5-day course).
Commercial insurance: Almirall Advantage card: eligible commercially insured patients may pay as little as $25. If the plan does not cover Klisyri, as low as $150 at retail or $95 at an Almirall Advantage Network pharmacy.
Uninsured or underinsured: Ask about the Almirall patient assistance pathway for uninsured patients.
Phone: 1-888-591-9860 · klisyri.com
A photosensitizing drug is applied in the office, then activated with blue or red light to treat actinic keratoses and field cancerization. Because PDT is delivered and billed as an in-office procedure, cost help runs through the treating practice and the manufacturer’s reimbursement team.
Used in skin cancer for: Actinic keratoses of the face and scalp; field therapy.
Commercial insurance: Ameluz PDT is billed under the medical benefit. Biofrontera’s reimbursement service verifies benefits, handles prior authorization, and works denials on the practice’s behalf.
Uninsured or underinsured: Ask the treating office to contact Biofrontera about assistance for patients who are uninsured or underinsured.
Phone: 1-844-426-3589 (1-844-4AMELUZ), ext. 7 for reimbursement; reimbursement@bfinc.com · us.ameluz.com
Used in skin cancer for: Actinic keratoses of the face, scalp, and upper extremities.
Commercial insurance: DUSA provides benefits verification and reimbursement support to treating practices; because Levulan PDT is delivered in the office, cost questions go through the practice.
Uninsured or underinsured: For the medication itself, ask about Sun Pharma’s patient assistance program for uninsured patients.
Status: FDA-approved but not currently marketed in the United States. Widely used for PDT in Europe.
Oral drugs that block the Hedgehog signaling pathway, used for basal cell carcinoma that cannot be treated with surgery or radiation, for metastatic disease, and in basal cell nevus (Gorlin) syndrome. Both approved agents are listed.
Used in skin cancer for: Metastatic basal cell carcinoma, or locally advanced disease after surgery/radiation or when those are not options.
Commercial insurance: Genentech Oncology Co-pay Assistance Program: eligible commercially insured patients may pay as little as $5 per prescription, up to $25,000 per year.
Uninsured or underinsured: Genentech Patient Foundation: free Erivedge for patients with no coverage and household income under $150,000 (higher for larger households), or whose out-of-pocket cost exceeds 7.5% of household income.
Phone: 1-877-436-3683 (Access Solutions); 1-888-941-3331 (Patient Foundation) · genentech-access.com
Used in skin cancer for: Locally advanced basal cell carcinoma that has recurred after surgery or radiation, or when those are not options.
Commercial insurance: Odomzo Co-Pay Program: eligible commercially insured patients may pay as little as $10 per month.
Uninsured or underinsured: Odomzo Patient Assistance Program: free medication for eligible uninsured or underinsured patients who meet income limits.
Phone: 1-877-636-6961 (1-877-ODOMZO-1) · odomzo.com/support-resources
Immunotherapy antibodies given by infusion. Across skin cancer they are used for melanoma (adjuvant and advanced), cutaneous squamous cell carcinoma, advanced basal cell carcinoma, and Merkel cell carcinoma. Every agent with a skin cancer indication is listed.
Used in skin cancer for: Metastatic Merkel cell carcinoma.
Commercial insurance: CoverOne Co-Pay Assistance: eligible commercially insured patients may pay $0 per infusion, up to $30,000 per year.
Uninsured or underinsured: CoverOne patient assistance: free Bavencio for eligible uninsured or underinsured patients.
Phone: 1-844-826-8371 (1-844-8COVER1) · coverone.com
Used in skin cancer for: Melanoma (adjuvant and advanced), cutaneous squamous cell carcinoma, Merkel cell carcinoma.
Commercial insurance: Merck Co-pay Assistance Program: eligible commercially insured patients may pay as little as $0 for Keytruda, up to an annual limit.
Uninsured or underinsured: Merck Patient Assistance Program: free Keytruda for eligible patients with no or inadequate coverage who meet income limits.
Phone: 1-855-257-3932 (Merck Access Program) · merckaccessprogram-keytruda.com
Used in skin cancer for: Advanced cutaneous squamous cell carcinoma, advanced basal cell carcinoma, and non-small cell lung cancer; studied in melanoma.
Commercial insurance: Libtayo Surround Copay Program: eligible commercially insured patients may pay as little as $0, up to $25,000 per year.
Uninsured or underinsured: Libtayo Surround Patient Assistance Program: free Libtayo for eligible patients who are uninsured or lack coverage for it.
Phone: 1-877-542-8296 (1-877-LIBTAYO), option 1 · libtayo.com
Used in skin cancer for: Melanoma (adjuvant and advanced); also sold as Opdualag, a fixed-dose combination with the LAG-3 inhibitor relatlimab.
Commercial insurance: BMS Access Support Co-pay Program: the patient pays the first $25 per dose and BMS covers the rest, up to $25,000 per product per calendar year.
Uninsured or underinsured: Bristol Myers Squibb Patient Assistance Foundation: free medicine for eligible uninsured patients in financial hardship.
Phone: 1-800-861-0048 (Access Support); 1-800-736-0003 (Patient Assistance Foundation) · bmsaccesssupport.com
Used in skin cancer for: BRAF V600 mutation-positive advanced melanoma, in combination with cobimetinib and vemurafenib.
Commercial insurance: Genentech Oncology Co-pay Assistance Program: as little as $5 per prescription/fill, up to $25,000 per year.
Uninsured or underinsured: Genentech Patient Foundation: free medicine on the same income test used for Erivedge.
Phone: 1-877-436-3683 (Access Solutions); 1-888-941-3331 (Patient Foundation) · genentech-access.com
Used in skin cancer for: Metastatic or recurrent locally advanced Merkel cell carcinoma.
Commercial insurance: IncyteCARES copay assistance for eligible commercially insured patients; an annual maximum applies and it is not valid with government insurance.
Uninsured or underinsured: IncyteCARES patient assistance: free drug for eligible uninsured or underinsured patients.
Phone: 1-855-452-5234 · incytecares.com
Checkpoint inhibitors that hit targets other than PD-1, almost always given together with a PD-1 drug for advanced or high-risk melanoma. All are Bristol Myers Squibb products and use the same two support programs.
Used in skin cancer for: Unresectable or metastatic melanoma.
Commercial insurance: BMS Access Support Co-pay Program: $25 per dose, then covered up to $25,000 per product per year.
Uninsured or underinsured: Bristol Myers Squibb Patient Assistance Foundation: free medicine for eligible uninsured patients.
Phone: 1-800-861-0048; 1-800-736-0003 · bmsaccesssupport.com
Used in skin cancer for: Melanoma (adjuvant and advanced), usually with nivolumab.
Commercial insurance: BMS Access Support Co-pay Program: $25 per dose, then covered up to $25,000 per product per year.
Uninsured or underinsured: Bristol Myers Squibb Patient Assistance Foundation: free medicine for eligible uninsured patients.
Phone: 1-800-861-0048; 1-800-736-0003 · bmsaccesssupport.com
Oral targeted-therapy pairs for melanoma that carries a BRAF V600 mutation, used both after surgery (adjuvant) and for advanced disease. All three approved combinations are listed.
Used in skin cancer for: Unresectable or metastatic BRAF V600E/K-mutant melanoma.
Commercial insurance: Pfizer Oncology Together Co-Pay Savings Program: eligible commercially insured patients may pay as little as $0 per month.
Uninsured or underinsured: Pfizer Patient Assistance Program: free Braftovi and Mektovi for eligible uninsured or underinsured patients who meet income limits.
Phone: 1-877-744-5675 · pfizeroncologytogether.com
Used in skin cancer for: Adjuvant and advanced BRAF V600-mutant melanoma.
Commercial insurance: Novartis Oncology Universal Co-Pay Program: eligible commercially insured patients may pay $0 per month; Novartis pays the balance up to $15,000 per product per year.
Uninsured or underinsured: Patient Assistance Now Oncology / Novartis Patient Assistance Foundation: free medication for eligible uninsured patients who meet income limits.
Phone: 1-877-577-7756 (Universal Co-Pay); 1-888-669-6682 (Patient Assistance Now Oncology) · patientassistancenow.com
Used in skin cancer for: BRAF V600-mutant advanced melanoma, alone or with atezolizumab (Tecentriq).
Commercial insurance: Genentech Oncology Co-pay Assistance Program: as little as $5 per prescription/fill, up to $25,000 per year.
Uninsured or underinsured: Genentech Patient Foundation: free medicine on the income test used for Erivedge.
Phone: 1-888-249-4918 (Access Solutions); 1-888-941-3331 (Patient Foundation) · genentech-access.com
Newer approaches for advanced melanoma: an oncolytic virus injected directly into tumors, and a one-time infusion of the patient’s own tumor-fighting immune cells. Both are delivered and billed as in-office or in-hospital procedures.
Used in skin cancer for: Advanced melanoma that has progressed after a PD-1 inhibitor (and a BRAF/MEK inhibitor if BRAF-mutant).
Commercial insurance: IovanceCares Copay Program covers out-of-pocket drug costs up to a program limit for commercially insured patients; case managers also help arrange travel and lodging.
Uninsured or underinsured: IovanceCares assesses eligibility for financial assistance for uninsured or underinsured patients.
Phone: 1-833-400-4682 · iovancecares.com
Used in skin cancer for: Injection into accessible skin, subcutaneous, and nodal melanoma lesions that have recurred after surgery.
Commercial insurance: Amgen FIRST STEP Program: commercially insured patients may lower their out-of-pocket cost for Imlygic; no income requirement.
Uninsured or underinsured: Amgen Safety Net Foundation: free Imlygic for eligible uninsured patients.
Phone: 1-866-264-2778 (1-866-AMG-ASST) · amgensupportplus.com
Melanoma of the eye is biologically distinct from skin melanoma and has one drug approved specifically for it.
Used in skin cancer for: HLA-A*02:01-positive unresectable or metastatic uveal melanoma.
Commercial insurance: KIMMTRAK Connect Copay Program: eligible commercially insured patients may pay as little as $0 per dose.
Uninsured or underinsured: KIMMTRAK Connect patient assistance: free drug for eligible uninsured or underinsured patients. Nurse case managers coordinate care and travel across treatment sites.
Phone: 1-844-775-2273 · kimmtrakconnect.com
Federal anti-kickback law bars manufacturer copay cards for anyone with government drug coverage. Independent charitable foundations fill that gap — but only when they have an open fund that matches your diagnosis. Funds open and close as donations allow, so check back if one is closed today.
The Financial & Insurance Navigator explains what each foundation covers and how the funding cycles work.
New drugs and new indications arrive faster than any static list. To check a specific medication — including chemoprevention drugs like acitretin, supportive-care medicines, or a drug used off-label — search these directories, or ask your cancer center’s financial navigator or specialty pharmacy to run a full assistance search. They do this every day.
Disclaimer: This page is general information for people in the United States and is not medical, financial, legal, or tax advice. Program names, dollar amounts, income limits, phone numbers, and eligibility rules change frequently and vary by plan and by state. Some drugs are used off-label in dermatology and coverage is not guaranteed. Confirm every detail directly with the program, your insurer, and your care team before acting. Listing a manufacturer program or an organization here is not an endorsement of any product or service, and no company has paid for or approved its inclusion.
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